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From medicalxpress.com

Gut bacteria influence responses to immunotherapy in mesothelioma patients, study finds

1 1

A cancer study has found that certain gut bacteria may influence whether or not a patient's immune system is successful in fighting mesothelioma, an aggressive form of cancer.

on Sep 5

From medicalxpress.com

UK identifies 4 cases of new mpox variant, the first cluster outside Africa

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British health officials say they have identified four cases of the new, more infectious version of mpox that first emerged in Congo, marking the first time the variant has caused a cluster of illness outside of Africa. Scientists said the risk to the public remains low.

on Mon, 1AM

From medicalxpress.com

New take on immunotherapy reinvigorates T cells by blocking uptake of energy-sapping cancer byproducts

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As cancer cells grow, they pump out metabolic byproducts such as lactic acid into the tumor microenvironment. Exhausted T cells—which have lost their cancer-fighting oomph—consume this lactic acid, which further saps their energy, according to new research from the University of Pittsburgh and...

on Sat, 1PM

From medicalxpress.com

Police interactions can increase epigenetic age in youth of color

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New research from the University of Minnesota shows that stress caused by negative interactions with police can increase epigenetic age, which is a biological indicator that can differ from chronological age. Previous research has shown this stress can age adults more quickly, but few studies...

on Nov 9

From medicalxpress.com

Custom alterations: Mending genes for long-lasting effects

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Gene-editing therapies—techniques that modify DNA to treat or prevent disease—have the potential to transform the field of drug development. By making precise edits to the genome, problematic genes could be modified or eliminated, representing long-lasting therapies for genetic disorders that...

on Nov 6

From medicalxpress.com

Could happy relationships hold the key to less stress in aging?

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Having happy intimate partners might not only lift our moods, but it also helps us manage stress, especially as we age, according to new research from the University of California, Davis.

on Nov 4

From medicalxpress.com

Prolonged sitting can sabotage health, even if you're young and exercise

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Between long commutes, Zoom-packed workdays and evenings of streaming and scrolling, Millennials now spend more than 60 hours per week sitting, potentially boosting their heart disease risk and accelerating other signs of aging, according to new University of Colorado Boulder and University of...

on Nov 2

From medicalxpress.com

Psoriasis patients can get clearer skin with at-home treatment instead of at doctors' offices, study suggests

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For decades, people with psoriasis have been treated in clinics with narrowband ultraviolet B phototherapy, or light therapy, to reduce sores, scales, and inflammation. Now, new research from the Perelman School of Medicine at the University of Pennsylvania shows that patients can improve their...

on Oct 27

From medicalxpress.com

Standing desks are bad for your health, according to a new study

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The global market for standing desks is booming, projected to reach US$12.6 billion by 2032 (£9.7 billion). These desks have been hailed as a simple fix for the health risks associated with sitting all day. However, recent research suggests that standing might not be the health booster many hoped for.

on Oct 27

From medicalxpress.com

Sound-based diagnostic system could deliver bedside blood test results in an hour

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Go to the doctor to provide a blood sample, and you're typically faced with a needle and syringe, and hours or even days of waiting to get results back from a lab. CU Boulder researchers hope to change that with a new handheld, sound-based diagnostic system able to deliver precise results in an...

on Oct 24

From medicalxpress.com

How vitamin D deficiency can lead to autoimmune diseases

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As Canadians brace for "vitamin D winter"—months when the sun's angle is too low to produce the vitamin in the skin—a McGill University study explains why vitamin D deficiency early in life is associated with a higher risk of autoimmune diseases.

on Oct 22

From medicalxpress.com

Snake research reveals insights into human intestinal regeneration

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All animals possess some capacity for repairing and replacing the lining of their intestines, a process called intestinal regeneration. In mammals, including humans, this constant but relatively minor turnover of cells helps the intestine keep up with the daily requirements of eating. It is...

on Oct 22

From medicalxpress.com

Systemic inflammation may play a role in how air pollution contributes to cognitive impairment

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Air pollution is often viewed as an outdoor hazard and a threat to respiratory health. Emerging research shows that air pollution may also affect our brain health. Fine particulate matter (PM2.5), is a complex mixture of many chemicals that can be inhaled deep into the lungs. While PM2.5...

on Oct 22

From medicalxpress.com

Survey suggests employers haven't a clue how their drug benefits are managed

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Most employers have little idea what the pharmacy benefit managers they hire do with the money they exchange for the medications used by their employees, according to a KFF survey.

on Oct 21

From medicalxpress.com

Learning without feedback: Neuroscientist helps uncover the influence of unsupervised learning on humans and machines

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Imagine a child visiting a farm and seeing sheep and goats for the first time. Their parent points out which is what, helping the child learn to distinguish between the two. But what happens when the child does not have that guidance on a return visit? Will they still be able to tell them apart?

on Oct 21

From medicalxpress.com

Study shows that Rett syndrome in females is not just less severe, but different

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A new UC Davis MIND Institute study offers critical insights into Rett syndrome, a rare genetic condition that affects mostly girls. The research reveals how this condition affects males and females differently, with symptoms progression linked to changes in gene responses in brain cells.

on Oct 19

From medicalxpress.com

Singling out distinct brain regions and mechanisms involved in our ability to pay attention

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The human brain is a complex organ with over 80 billion neurons. But it can still trip up when it comes to multitasking. Trying to send an email at the same time as talking to someone can almost be enough to short-circuit our synapses, leaving us distracted and prone to making mistakes.

on Oct 19

From medicalxpress.com

Study finds RSV vaccine highly effective in protecting older adults against severe disease, hospitalization and death

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A multi-state study, published in The Lancet, is one of the first real world data analyses of the effectiveness of the RSV—short for respiratory syncytial virus—vaccine. VISION Network researchers report that across the board these vaccines were highly effective in older adults, even those with...

on Oct 18

From medicalxpress.com

Study shows playing video games may improve cognitive performance

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Playing video games may boost your cognitive abilities and exercise can play a role in improving your mental health, but not the other way around, a large-scale study has found.

on Oct 18

From medicalxpress.com

High-potency cannabis use is tied to epigenetic changes, study suggests

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A study published in Molecular Psychiatry is the first to suggest that the use of high-potency cannabis leaves a distinct mark on DNA, providing valuable insights into the biological impact of cannabis use. High-potency cannabis is defined as having Delta-9-tetrahydrocannabinol (THC) content of...

on Oct 18

From medicalxpress.com

COVID study reveals virus-induced inflammation during pregnancy, redefines vertical transmission

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A new Cleveland Clinic-led study published in The EMBO Journal shows that mild and asymptomatic SARS-CoV-2 infections can trigger immune responses in a pregnant individual that may cause serious inflammatory responses in the developing fetus.

on Oct 18

From medicalxpress.com

Researchers show tumor evolution is written in the genome

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Using a system of genetic barcodes and a novel single-cell sequencing method, a research team at the Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology) in Milan has developed an approach to identify cells responsible for initiating tumors and metastasis, particularly in breast cancer.

on Oct 18

From medicalxpress.com

Study finds genetics, not lifestyle, is a major cause of gout

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A major international study has found that gout is a chronic illness in which genetics is a major cause, rather than the lifestyle choices of the sufferer.

on Oct 18

From medicalxpress.com

Clean air and climate policies provide health benefits in New York City

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A new study analyzes the links between the enactment of major air pollution and climate policies in New York City and significant improvement in air quality during the period 1998–2021. It finds a cumulative beneficial effect of these policies both city-wide and among residents residing in...

on Oct 18

From medicalxpress.com

People regularly experiencing brighter nights and darker days have higher mortality risk, suggests study

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A team of biologists, medical researchers and sleep specialists from several institutions in Australia, the U.S. and the U.K. has found that people who regularly experience brighter nights and/or darker days tend to have a higher mortality risk.

on Oct 18

From medicalxpress.com

Bursts of exercise boost cognitive function, neuroscientists find

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Decades of exercise research data support the common view that steady workouts over the long haul produce not only physical benefits but also improved brain function. But what about single bursts of exercise? A team of scientists at UC Santa Barbara has taken a closer look.

on Oct 18

From medicalxpress.com

Scientists identify key protein in the inflammatory pathway driving fatty liver disease

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Scientists at the Agency for Science, Technology and Research (A*STAR) and the Shanghai Institute of Immunology (SII), along with their international collaborators, have dissected the key signaling mechanism driving inflammation in metabolic dysfunction-associated steatohepatitis (MASH), through...

on Oct 18

From medicalxpress.com

New research confirms location of pseudoautosomal region boundary between the two sex chromosomes

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In the 1980s, scientists knew little about the X and Y chromosomes. What they did understand was that every cell in the body contains 23 pairs of chromosomes. Each of these pairs is similar, except one. While females typically have two X chromosomes, males have one X chromosome and one Y...

on Oct 18

From medicalxpress.com

New type of insulin that switches on and off could help diabetics avoid sudden drops in blood sugar levels

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A modified insulin that can prevent sudden drops in blood sugar has been demonstrated in laboratory experiments and animal models, reports a paper in Nature. This could provide a more flexible way to supplement insulin for individuals with diabetes and reduce sudden drops in blood glucose.

on Oct 18

From medicalxpress.com

Neuroscientists discover a mechanism that can reactivate dormant neural stem cells

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An international team of neuroscientists, led by Duke-NUS Medical School, have uncovered a mechanism that controls the reactivation of neural stem cells, which are crucial for repairing and regenerating brain cells.

on Oct 18

From medicalxpress.com

COVID-19 linked to type 2 diabetes onset in children

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Pediatric patients aged 10 to 19 years old diagnosed with COVID-19 have a higher risk of new-onset type 2 diabetes within six months compared to those diagnosed with other respiratory infections, according to researchers at Case Western Reserve University School of Medicine.

on Oct 18

From medicalxpress.com

Pandemic preparedness and response: Are we better off than pre-COVID?

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Two articles by University of Otago, Christchurch, researchers in this week's New Zealand Medical Journal (NZMJ) raise concerns about global and local readiness to deal with a future pandemic—with one saying we risk falling into "a cycle of panic and neglect" and the other exposing self-reported...

on Oct 18

From medicalxpress.com

Many more lives could have been saved with convalescent COVID-19 plasma

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Thousands more U.S. lives could have been saved with the use of COVID-19 convalescent plasma (CCP), according to a study published online Oct. 1 in the Proceedings of the National Academy of Sciences.

on Oct 17

From medicalxpress.com

California passes law allowing Dutch-style cannabis cafes

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Starting next year, diners in the western US state of California can smoke cannabis at certain restaurants, thanks to a new law allowing for "cannabis cafes" akin to those popularized in the Netherlands.

on Oct 17

From medicalxpress.com

Cheek cell–based epigenetic clock allows scientists to estimate mortality risk

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We don't all age at the same rate. But while some supercentenarians may age exceptionally slowly due to winning the genetics jackpot, a plethora of behavioral and lifestyle factors are known to speed up aging, including stress, poor sleep, poor nutrition, smoking, and alcohol. Since such...

on Oct 17

From medicalxpress.com

Scientists discover unexpected link between genes involved in human brain evolution and developmental disorders

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The human brain's remarkably prolonged development is unique among mammals and is thought to contribute to our advanced learning abilities. Disruptions in this process may explain certain neurodevelopmental diseases.

on Oct 17

From medicalxpress.com

1 in 4 adults suspect undiagnosed ADHD, survey finds

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Attention deficit/hyperactivity disorder—also known as ADHD—is typically thought of as a childhood condition. But more adults are realizing that their struggles with attention, focus and restlessness could in fact be undiagnosed ADHD, thanks in large part to trending social media videos racking...

on Oct 17

From medicalxpress.com

Heart failure, atrial fibrillation and coronary heart disease linked to cognitive impairment

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Three common cardiovascular diseases in adults—heart failure, atrial fibrillation and coronary heart disease—are linked to cognitive impairment and increased risk of dementia, according to "Cardiac Contributions to Brain Health," a new scientific statement from the American Heart Association...

on Oct 17

From medicalxpress.com

Commonly used arm positions can substantially overestimate blood pressure readings, study finds

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A study led by Johns Hopkins Medicine researchers concludes that commonly used ways of positioning the patient's arm during blood pressure (BP) screenings can substantially overestimate test results and may lead to a misdiagnosis of hypertension.

on Oct 17

From medicalxpress.com

Ultra-powered MRI scans show damage to brain's 'control center' is behind long-lasting COVID-19 symptoms

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Damage to the brainstem—the brain's 'control center'—is behind long-lasting physical and psychiatric effects of severe COVID-19 infection, a study suggests.

on Oct 17

From medicalxpress.com

Magnetically regulated gene therapy tech offers precise brain-circuit control

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A new technology enables the control of specific brain circuits non-invasively with magnetic fields, according to a preclinical study from researchers at Weill Cornell Medicine, The Rockefeller University and the Icahn School of Medicine at Mount Sinai. The technology holds promise as a powerful...

on Oct 17

From medicalxpress.com

Study finds our attention shifts influenced by rewards, not habits

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The mobile phone is often blamed for drowning us in information and stealing our attention. But it is rather our inner reward system that our phones and tech companies utilize, shows new research from the University of Copenhagen.

on Oct 17

From medicalxpress.com

Our animal inheritance: Humans 'prick up their ears,' too, when they hear interesting sounds

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Many animals, including dogs, cats and various species of monkeys, will move their ears to better focus their attention on a novel sound. That humans also have this capability was not known until now. A research team based in Saarland has demonstrated for the first time that we make minute,...

on Oct 16

From medicalxpress.com

Researchers find high school IQ predicts drinking habits

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A person's IQ during high school is predictive of alcohol consumption later in life, according to a study by UT Southwestern Medical Center researchers published in Alcohol and Alcoholism. Participants with higher IQ levels were significantly more likely to be moderate or heavy drinkers, as...

on Oct 16

From medicalxpress.com

Are dental practices out of control in the United States?

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A series of recently published opinions and letters in JAMA Internal Medicine present varying perspectives on the current state of US dental care all emphasize the need for evidence-based practices and changes in economic models.

on Oct 16

From medicalxpress.com

Engrams emerging as the basic unit of memory

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Though scientist Richard Semon introduced the concept of the "engram" 115 years ago to posit a neural basis for memory, direct evidence for engrams has only begun to accumulate recently as sophisticated technologies and methods have become available. In a new review in Science, Professors Susumu...

on Oct 10

From medicalxpress.com

Fatty acids found in meat and poultry may be beneficial to human metabolism

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Consuming fish oil or seafood along with their omega-3 fatty acids—good. Consuming too much red meat along with its omega-6 fatty acids—bad. In reality, however, the impact of arachidonic acid, an omega-6 polyunsaturated fat found only in animal products, upon human health remains a complicated,...

on Oct 10

From medicalxpress.com

Analysis finds extreme rainfall linked to heightened risk of heart and lung disease deaths

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Extreme rainfall events are associated with an increased risk of death from all causes as well as from heart and lung diseases, finds an analysis of data from 34 countries and regions published by The BMJ.

on Oct 10

From medicalxpress.com

World's first individual gene mutation test for predicting risk of sudden cardiac death

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Scientists at the Victor Chang Cardiac Research Institute, working with colleagues at the Vanderbilt University Medical Center, have developed a world-first, individualized risk prediction tool for people suffering from a type of heart arrhythmia that can cause sudden cardiac arrest.

on Oct 10

From medicalxpress.com

Newly discovered COVID vaccine targets may last longer

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Melbourne researchers have discovered more than 200 new vaccine target candidates from the COVID-19 virus, SARS-CoV-2, that could lead to the development of vaccines with a longer lasting broader immunity than existing vaccinations.

on Oct 10