#prot
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From nih.gov
An algorithm for peptide de novo sequencing from a group of SILAC labeled MS/MS spectra - PubMed
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Shotgun proteomics coupled with high-performance liquid chromatography and mass spectrometry has been instrumental in identifying proteins in complex mixtures. Effective computational approaches are required to automate the spectra interpretation process to handle the vast amount of data collected i …
21h ago
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From nih.gov
On the question of correct use of replicates in quantitative label-free proteomics - PubMed
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Label-free quantitation is the most popular method in proteomics for assessing changes in protein concentrations. However, practical aspects like the optimal use of technical replicates, the impact of removing low-identified protein runs, and the effect of combining information from technical replic …
19h ago
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