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From chemrxiv.org

Charge Transfer and Recombination Pathways through Fullerene Guests in Porphyrin-based MOFs

1 1

Porphyrin-based metal organic frameworks (MOFs) offer a unique platform for building porous donor-acceptor networks that exhibit conductive behavior and/or long-lived charge separation upon incorporation of electron acceptor guest species. Here, porphyrin-based MOFs, PCN-222(H2) and PCN-222(Zn),...

5h ago

From chemrxiv.org

Revisiting the effect of trypsin digestion buffers on artificial deamidation

1 1

Deamidation of asparagine and glutamine residues occurs spontaneously, is influenced by pH, temperature, and incubation time, and can be accelerated by adjacent amino acid residues. Incubation conditions used for proteolytic digestion in bottom-up proteomic studies can induce significant...

#prot #proteomics

8h ago

From chemrxiv.org

Focussed Microwave Assisted Synthesis of Multifunctional Eu doped Gd-MOF based Optochemical Sensor for the Sensing of pH and Heavy Metal Ions

1 1

Rare-earth Metal-organic frameworks (RE-MOFs) are known for their efficient photoluminescent properties and has been synthesized by various time consuming synthetic methodologies. In this work, we have addressed the synthesis of RE-MOFs via a novel Monomode microwave assisted route to yield MOFs...

14h ago

From chemrxiv.org

A combined experimental and computational exploration of heteroleptic cis-Pd2L2L’2 coordination cages through geometric complementarity

1 1

Heteroleptic (mixed-ligand) coordination cages are of interest as host systems with more structurally and functionally complex cavities than homoleptic architectures. The design of heteroleptic cages, however, is far from trivial. In this work, we experimentally probed the self-assembly of...

on Sep 6

From chemrxiv.org

Optically Transparent Porous Salt Thin Films Enable In Situ Characterization of Structure- and Depth-Dependent Post-Synthetic Metalation

1 2

Post-synthetic metalation and metathesis chemistry are central to rational synthesis of metal-organic frameworks (MOFs) that are unavailable by direct self-assembly. The rate, extent, and distribution of post-synthetically modified sites is challenging to characterize due to the...

on Sep 5

From chemrxiv.org

High-resolution structure of Zn3(HOTP)2 (HOTP = hexaoxidotriphenylene), a three-dimensional conductive MOF

0 1

Although two-dimensional (2D) electrically conducting metal-organic frameworks (cMOFs) have become prominent due to their numerous potential applications, their structures are often implied or assumed from rather crude powder X-ray diffraction data. Indeed, exceedingly few examples exist of...

on Wed, 2PM

From chemrxiv.org

Templated tube growth about a reactive gas plume, the pharaoh’s serpent reaction

0 1

The pharaoh’s serpent reaction, the thermodecomposition of mercury thiocyanate in air, is a classic chemical demonstration. We analyse and characterize the reaction products, composed of two different phases, graphitic carbon nitride, C3N4 and metacinnabar, HgS. We show that two growth modes are...

on Tue, 9PM

From chemrxiv.org

Stereochemistry-aware string-based molecular generation

0 1

This study investigates the impact of incorporating stereochemical information, a crucial aspect of computational drug discovery and materials design, in molecular generative modelling. We present a comprehensive comparison of stereochemistry-aware and conventionally stereochemistry-unaware...

on Sat, 7PM

From chemrxiv.org

Open-source and FAIR Research Software for Proteomics

0 1

Scientific discovery relies on innovative software as much as experimental methods, especially in proteomics, where computational tools are essential for mass spectrometer setup, data analysis, and interpretation. Since the introduction of SEQUEST, proteomics software has grown into a complex...

on Sat, 2PM

From chemrxiv.org

Accelerating CO₂ Direct Air Capture Screening for Metal-Organic Frameworks with a Transferable Machine Learning Force Field

0 0

Direct air capture (DAC) of CO₂ is necessary for climate change mitigation, but it faces challenges from low atmospheric CO₂ concentrations and competition from water vapor. Metal-organic frameworks (MOFs) are attractive candidates for DAC owing to their exceptionally high surface area, tunable...

on Dec 13

From chemrxiv.org

An Electrically Conducting, Redox-Complementary Dual-Ligand 2D Graphitic MOF with Orthogonal Charge Transport Pathways

0 0

Owing to their diverse potential applications in modern electronics and energy technologies, electrically conducting metal–organic frameworks (MOFs) have emerged as one of the most coveted functional materials of the twenty-first century. The electrical conductivity is a product of frameworks’...

on Dec 12

From chemrxiv.org

Bottom-Up Computational Design of Shape-Selective Organic Macrocycles for Humid CO2 Capture

0 0

The capture of carbon dioxide (CO2) emissions using porous solids is challenging because polarized water molecules bind more strongly in most materials than non-polarized CO2 molecules. This is a challenge for both flue gas capture and for direct air capture alike. We developed a bottom-up...

on Dec 12

From chemrxiv.org

CoRE MOF DB: a curated experimental metal-organic framework database with machine-learned properties for integrated material-process screening

0 0

We present an updated version of the CoRE MOF database, which includes a curated set of computation-ready MOF crystal structures designed for high-throughput computational materials discovery. Data collection and curation procedures were improved from the previous version to enable more frequent...

on Dec 12

From chemrxiv.org

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Metal-Organic Frameworks

0 0

In the past two decades, metal-organic frameworks (MOFs) have evolved from uses in catalysis and gas storage to exciting applications in biomedicine, particularly in drug delivery. Initially, MOFs were primarily used to deliver small molecules, but recent innovations have shifted focus toward...

on Dec 12

From chemrxiv.org

Evaluation of Membrane Mimetics for the Native Ion Mobility – Mass Spectrometry Analysis of Membrane Proteins

0 0

Membrane protein (MP) structures and functions are intricately linked to their surrounding membrane environments and their respective lipid compositions in addition to influences exerted by unique membrane microdomains (i.e., lipid rafts). Owing to the complexity of their native environments,...

on Dec 11

From chemrxiv.org

Exploring the Atomic-Scale Interactions at the Interface of Reducible Oxide and Ruthenium Nanocatalyst in Ammonia Decomposition

0 0

Reconstructing interfaces at the atomic level through interactions between precious metal catalysts and highly stable oxides opens new possibilities for enhancing inherent catalytic properties. Here, we investigate the interactions between metal oxide particles and Ru nanoparticles formed...

on Dec 10

From chemrxiv.org

Physics-Based Synthetic Data Model for Automated Segmentation in Catalysis Microscopy

0 0

In catalysis research, the amount of microscopy data acquired when imaging dynamic processes is often too much for non-automated quantitative analysis. Developing machine learned segmentation models is challenged by the requirement of high-quality annotated training data. We thus substitute...

on Dec 10

From chemrxiv.org

Identification of an Allene Warhead that Selectively Targets a Histidine Residue in the Escherichia coli Oxidoreductase Enzyme DsbA

0 0

Covalent modification of protein targets has application in both protein activity profiling and in drug discovery. Covalent warheads typically contain an electrophile that selectively reacts with nucleophilic residues in a protein target, such as cysteine, serine and threonine. Expanding this to...

on Dec 9

From chemrxiv.org

A Self-Driving Lab for Nano- and Advanced Materials Synthesis

0 0

The recent emergence of self-driving labs (SDL) and material acceleration platforms (MAPs) demonstrates the ability of these systems to change the way chemistry and material syntheses will be performed in the future. Especially in conjunction with nano and advanced materials which are generally...

on Dec 9

From chemrxiv.org

Ideal Molecular Sieving with a Dense MOF for Helium Upgrading with Highly Diffusion Selective Mixed Matrix Membranes

0 0

Helium is one of the most critical resources of our planet, as it is a finite resource, cannot be produced from radioactive decay in sufficient amounts and escapes our atmosphere, while being extraordinarily important for high tech applications in research and medicine. We demonstrate a concept...

on Dec 5

From chemrxiv.org

Cyclooctadiene-Derived Cage-Divergent Synthesis of Heteroadamantanes and Alternative Polycyclic Systems

0 1

We report a scalable, cage-divergent synthesis of oxygen- and nitrogen-doped adamantanes and related tricyclic morpholine mimetics from readily available cycloocta-1,5-diene. This approach enables multigram quantities of such products, which were previously hardly accessible or even unavailable,...

on Dec 4

From chemrxiv.org

Regulating N-atom Number in Donor-Acceptor Units Covalent Organic Framework (COF) for Photocatalytic H2O2 production from Sunlight and Seawater

0 0

The development of photocatalyst by tunning the Donor-Acceptor (D-A) properties into the covalent organic frameworks that regulate the photocatalytic production of highly valued chemical H2O2 by harvesting natural resources such as sunlight and seawater is one of the challenging tasks. In this...

on Dec 3

From chemrxiv.org

Dynamic supramolecular fluids containing azobenzene tailor sodium-based metal organic frameworks into helical and flower morphology

0 0

Multiphasic structuring has emerged as a transformative strategy for controlling self-assembly at the nanoscale, enabling the creation of materials with unprecedented complexity and functionality. By introducing azobenzene-based supramolecular fluids into solvothermal reactions, we direct the...

on Dec 2

From chemrxiv.org

Development of an Automated Workflow for Screening the Assembly and Host-Guest Behaviour of Metal-Organic Cages towards Accelerated Discovery

0 0

Metal-organic cages (MOCs) have emerged as a class of self-assembled materials with promising applications in chemical purifications, sensing, and catalysis. Their potential is, however, hampered by challenges in the targeted design and realization of MOCs with desirable properties. MOC...

on Nov 29

From chemrxiv.org

imzML Writer: An Easy-to-Use Python Pipeline for Conversion of Continuously Acquired Raw Mass Spectrometry Imaging Files to imzML Format

0 0

Mass spectrometry imaging (MSI) is a powerful tool which reveals the contextual distribution of biomolecules in tissues. Acquiring these images involves collecting an information-rich mass spectrum for each pixel of the ion image, which results in large datasets typically exceeding 1 GB. To...

on Nov 29

From chemrxiv.org

Dynamic and Patternable MOF-Based Liquid Photonic Crystals for Metameric Displays

0 0

We present the development of dynamic and patternable liquid photonic crystals (LPCs) based on zeolitic imidazolate framework-8 (ZIF-8) crystals, an approach that exploits the unique optical and structural properties of metal-organic frameworks (MOFs). By utilizing monodisperse ZIF-8 particles...

on Nov 29

From chemrxiv.org

Anisotropic Node Distortions in Amorphous MOFs: Low Valent Zr Sites as Catalytic Hotspots

0 0

We introduce a new approach to defect engineering in Zr-based metal-organic frameworks (Zr-MOFs), aiming to reduce Zr site valency while preserving high node connectivity. Using a rapid heat treatment (RHT) in humid air, O-vacancies were created in DUT-67 through cluster dehydration. Unlike...

on Nov 28

From chemrxiv.org

Adapting a trapped ion mobility spectrometry-Q-TOF for high m/z native mass spectrometry and surface-induced dissociation

0 0

Native mass spectrometry (nMS) is increasingly popular for studying intact protein quaternary structure. When coupled with ion mobility, which separates ions based on their size, charge, and shape, it provides additional structural information on the protein complex of interest. In this study,...

on Nov 26

From chemrxiv.org

Improvements in glycoproteomics through architecture changes to the Orbitrap Tribrid MS platform

0 0

Hardware changes introduced on the Orbitrap Ascend MultiOmics Tribrid MS include dual ion routing multipoles (IRMs) that can enable parallelized accumulation, dissociation, and Orbitrap mass analysis of three separate ion populations. The balance between these instrument functions is especially...

on Nov 26

From chemrxiv.org

Engineering Photoswitching Dynamics in 3D Photochromic Metal-Organic Frameworks through Metal-Organic Polyhedron Design

0 0

Metal-organic polyhedra (MOPs) are versatile supramolecular building blocks for the design of highly porous frame-works by reticular assembly because of their diverse geometries, multiple degrees of freedom regarding functionaliza-tion, and accessible metal sites. Lipophilic functionalization is...

on Nov 25

From chemrxiv.org

Examining proton conductivity of metal-organic frameworks by means of machine learning

0 0

The tunable structure of metal–organic frameworks (MOFs) is an ideal platform to meet contradictory requirements for proton exchange membranes: a key component of fuel cells. Nonetheless, rational design of proton-conducting MOFs remains a challenge owing to the intricate structure–property...

on Nov 25

From chemrxiv.org

Hybrid Materials: Next-Generation Engineering Materials

0 0

Hybrid organic-inorganic materials represent a fascinating class of compounds that combine the unique properties of both organic compounds and inorganic materials. These hybrids leverage the versatility of organic molecules - such as their flexibility and functionality - alongside the robustness...

on Nov 22

From chemrxiv.org

Ab initio predictions of adsorption in flexible metal-organic frameworks for water harvesting applications.

0 0

Recently, metal-organic frameworks like MOF-303 and MOF-LA2-1 have demonstrated exceptional performance for water harvesting applications. To enable a reticular design of such materials, an accurate prediction of the adsorption properties with chemical accuracy and fully accounting for the...

on Nov 20

From chemrxiv.org

Synthesis of Macrocycles via Orthogonal Bond Cleavage of the Pores in Covalent Organic Frameworks

0 0

Control of selectivity in organic synthesis is essential for guiding chemical reactions towards a desired product when multiple outcomes are possible. Since organic reactions can often yield a range of products, selectivity control ensures that the target product is favoured over others. Herein,...

on Nov 20

From chemrxiv.org

Laser Induced 3D Printed Graphene Enhanced Thermoplastic Polyurethane Structure for Improved Anisotropy and Photothermal and Electrothermal De-icing Performance

0 0

A laser induction process was applied to a previously developed FDM 3D-printed graphene enhanced thermoplastic polyurethane structure. Notably, the orientation of graphene flakes and the integrity of the double-layer structure were preserved during the decomposition of the polymer matrix,...

on Nov 20

From chemrxiv.org

Biomass-based sustainable covalent organic framework (COF) anode for high-performance LIBs

0 0

COFs with reversible redox behaviours are promising lithium-ion batteries (LIBs) electrode materials. However, traditional COFs are synthesized from organic monomers primarily derived from fossil fuels, significantly hindering the sustainable development of COF materials. In this study, a novel...

on Nov 19

From chemrxiv.org

Phase Transformations in MOFs Induced by Adsorbate Exchange

0 0

Deformation of nanoporous materials induced by gas adsorption is a ubiquitous phenomenon that plays important role in adsorption separations, gas and energy storage, nanosensors, actuators, secondary gas recovery and carbon dioxide sequestration in coal and shale reservoirs. One of the most...

on Nov 19

From chemrxiv.org

Molecular diffusion enhanced performance evaluation of metal-organic frameworks for CO2 capture

0 0

Molecular diffusion is a fundamental property that limits the performance of solid sorbents in carbon dioxide capture and separation applications. Unique to each sorbent, gas diffusion is determined by the physical and chemical interactions that occur between the gas molecules and a sorbent’s...

on Nov 19

From chemrxiv.org

Porous halogen-bonded frameworks assembled through hetero-polytopic ion pair templation

0 0

Halogen-bonding (XB) interactions have been extensively studied in the preparation of crystalline frameworks, yet porous 3D framework materials built on XBs remain elusive. The donor-acceptor interactions are strengthened by use of anionic XB acceptors; however, the requisite charge-balancing...

on Nov 18

From chemrxiv.org

Structure and Synthesizability of Iron-Sulfur Metal-Organic Frameworks

0 0

Sulfur-based metal-organic frameworks (MOFs) and coordination polymers (CPs) are an emerging class of hybrid materials that have received growing attention due to their potential magnetic, conductive, and catalytic properties with applications in electrocatalysis and energy storage. In this...

on Nov 18

From chemrxiv.org

De novo glycan annotation of mass spectrometry data

0 0

Carbohydrates are fundamental molecules of life and are involved in virtually all biological processes. The chemical diversity of glycans – carbohydrate chains – enables these diverse functions, but also challenges analytics. Mass spectrometry (MS) is a powerful approach to resolve and identify...

on Nov 18

From chemrxiv.org

A Chiral Metal-Organic Framework Fluorescent Sensor incorporating H8-BINOL

0 0

Fluorescent chiral chemical sensors with high enantioselectivity enable the identification of enantiomers in an inexpensive, accessible, and rapid manner even at low analyte concentrations. The discrimination of enantiomeric systems is of high importance in pharmaceutical and health sciences due...

on Nov 17

From chemrxiv.org

Adaptive Representation of Molecules and Materials in Bayesian Optimization

0 0

Bayesian optimization (BO) is increasingly used in molecular optimization and in guiding self-driving laboratories for automated materials discovery. A crucial aspect of BO is how molecules and materials are represented as feature vectors, where both the completeness and compactness of these...

on Nov 15

From chemrxiv.org

A Multipoint Validation of Quantification in Capillary Electrophoresis Mass Spectrometry Proteomics: Isobaric Multiplexing with Tandem Mass Tags

0 0

Multiplexing quantification using isobaric barcoding has gained traction in single-cell mass spectrometry (MS), both in nano-flow liquid chromatography (nanoLC) and capillary electrophoresis (CE). In nanoLC-MS, ratio compression from isobaric interferences challenges the accuracy of...

on Nov 14

From chemrxiv.org

On the mechanism of electron-beam-induced structural degradation in ZIF-8 and its electron dose tolerance

0 0

Zeolitic-imidazolate frameworks (ZIFs) are crystalline microporous materials with promising potential for gas adsorption and catalysis application. Further research advances include studies on integrating ZIFs into nanodevice concepts. In detail for the application, e.g., electron-beam-assisted...

on Nov 13

From chemrxiv.org

Carbon footprint comparison of liquid organic hydrogen carriers cycled thermochemically and electrochemically

0 0

Hydrogen (H2) has been proposed as a way to store energy for long durations with minimal carbon footprint. The challenges of using H2 to store energy are that it has very low volumetric density and diffuses rapidly through container walls. Liquid organic hydrogen carriers (LOHCs) have been...

on Nov 12

From chemrxiv.org

Analysis of Hydrophobicity in Micropores of Metal-Organic Framework Materials

0 0

Water molecules in hydrophobic micropores of Metal Organic Framework (MOF) materials show disparate behavior in adsorption equilibrium. Ranging from behavior indicative of large, Type V uptakes occurring at low relative pressure, to Type III equilibrium where little water is adsorbed, this...

on Nov 11

From chemrxiv.org

Versatile sulfidation of a metal-organic framework via heterolytic splitting of organo sulfides at distorted Zr-nodes

0 0

The sulfidation of metal oxides is critical to the creation of catalyst active sites for industrially-relevant reactions, but occurs at high temperatures for refractory oxides like zirconia. Here, we investigate sulfidation of the structurally-well-defined, Zr-based metal-organic framework (MOF)...

on Nov 11

From chemrxiv.org

New Isostructural Family of Mixed-Metal Na-M(III)-MOFs Based on Glycolic Acid

0 0

A series of new isostructural metal–organic frameworks based on trivalent metal ions (Al, Fe, Ga), Na+ ions and glycolate ions as the linker molecules, denoted as M-CAU-64, with the framework composition [M(III)Na(H2O)2(C2H2O3)2] · x H2O were obtained using high-throughput methods. The crystal...

on Nov 11

From chemrxiv.org

Examining proton conductivity of metal-organic frameworks by means of machine learning

0 0

The tunable structure of metal–organic frameworks (MOFs) is an ideal platform to achieve contradictory requirements for proton exchange membranes, a key component of fuel cells. However, the rational design of proton-conducting MOFs remains a challenge owing to the intricate structure-property...

on Nov 8