From biorxiv.org

Cooperative motility emerges in crowds of T cells but not neutrophils

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T cells are among the most motile immune cells in the body, and their migration into and within tissues is key to their function. Remarkably, T cells can maintain their motility even in highly crowded environments like the densely packed T cell areas of lymphoid organs, but how they do so...

#cell #Dynamics

5h ago

From nih.gov

FMNL1 and mDia1 promote efficient T cell migration through complex environments via distinct mechanisms - PubMed

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Lymphocyte trafficking and migration through tissues is critical for adaptive immune function and, to perform their roles, T cells must be able to navigate through diverse tissue environments that present a range of mechanical challenges. T cells predominantly express two members of the formin famil …

#cell #actin #mechanical #cellmigration

14h ago