From biorxiv.org
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Understanding the phenotypic transitions of cancer cells is crucial for elucidating tumor progression mechanisms, particularly the transition from a non-invasive spheroid phenotype to an invasive network phenotype. We developed an agent-based model (ABM) using Compucell3D, an open-source...
13h ago
From arxiv.org
Phenotype-structuring of non-local kinetic models of cell migration driven by environmental sensing
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The capability of cells to form surface extensions, which enable them to non-locally probe the surrounding environment, plays a key role in cell migration. The existing mathematical models for collective migration of cell populations driven by this non-local form of environmental sensing rely on...
14h ago
From arxiv.org
Spiral waves speed up cell cycle oscillations in the frog cytoplasm
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Spiral waves are a well-known phenomenon in excitable media, playing critical roles in biological systems such as cardiac tissues, where they are involved in arrhythmias, and in slime molds, where they guide collective cell migration. However, their presence in the cytoplasm of cells has not...
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