From arxiv.org
Spiral waves speed up cell cycle oscillations in the frog cytoplasm
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Spiral waves are a well-known phenomenon in excitable media, playing critical roles in biological systems such as cardiac tissues, where they are involved in arrhythmias, and in slime molds, where they guide collective cell migration. However, their presence in the cytoplasm of cells has not...
#q #cell #nlin #physics #cellmigration
23h ago
From nih.gov
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The role of immune cells is crucial in nerve regeneration following spinal cord injury. Kif15, a member of the kinesin family, has been shown to enhance macrophage phagocytosis. This study investigates the impact of Kif15 deficiency on immune cells in zebrafish with spinal cord injury. Using kif15 m …
23h ago
From nih.gov
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The study reveals that the heterodimeric kinesin-2 motor KIF3AC and its adaptor RCP are crucial for polarized formation of focal adhesions at the front of migrating fibroblasts. KIF3AC and RCP associate with intracellularly recycling integrin to promote its return to the cell surface after its endoc …
#kinesin #adhesion #cellmigration
10h ago
From nih.gov
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The extracellular matrix (ECM) is a complex meshwork comprising over 100 proteins. It serves as an adhesive substrate for cells and, hence, plays critical roles in health and disease. We have recently identified a novel ECM protein, SNED1, and have found that it is required for neural crest cell mig …
#ECM #cellmigration #extracellular
11h ago
From biorxiv.org
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The recycling of integrin endocytosed during focal adhesion (FA) disassembly is critical for cell migration and contributes to the polarized formation of new FAs toward the leading edge. How this occurs is unclear. Here, we sought to identify the kinesin motor protein(s) that is involved in...
#kinesin #adhesion #cellmigration
10h ago
From biorxiv.org
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Three copper(II) complexes containing 1,10-phenanthroline ([CuCl2(phen)].4H2O), neocuproine ([CuCl2(neo)].4H2O) and tetramethyl-phenanthroline ([CuCl2(tmp)].4H2O) as the primary ligand and another three copper(II) complexes with the L-Ala-Phe dipeptide as an auxiliary ligand:...
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