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#force

5 15 Toot LinkedIn
A chart of hourly posts over the last week (for big screens). A chart of hourly posts over the last week (for small screens).

1

From nih.gov

Emergence of biphasic versus monotonic response of actin retrograde flow and cell traction force with varying substrate rigidity - PubMed

1 1

The transmission of cytoskeletal forces to the extracellular matrix through focal adhesion complexes is essential for a multitude of biological processes, such as cell migration, cell differentiation, tissue development, and cancer progression, among others. During migration, focal adhesions arrest …

#actin #force #Forces #cytoskeletal

14h ago


1

From biorxiv.org

Mechanical force regulates the inhibitory function of PD-1

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The immune checkpoint molecule, programmed cell death 1 (PD-1), plays a pivotal role in regulating T-cell function. Upon binding to its ligands, PD-L1 or PD-L2, PD-1 suppresses T-cell receptor signaling, thereby preventing T-cell activation, making it a critical target in cancer immunotherapy....

#cell #force #mechanical

23h ago

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