#celldivision

From arxiv.org

A self-organised liquid reaction container for cellular memory

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Epigenetic inheritance during cell division is essential for preserving cell identity by stabilizing the overall chromatin organisation.Heterochromatin,the condensed and transcriptionally silent fraction of chromatin,is marked by specific epigenetic modifications that are diluted during each...

#cell #physics #celldivision

23h ago

From biorxiv.org

Gene expression is globally regulated by interacting nucleobase supply and mRNA composition demand: a mechanism disrupted by multiple disease states and drug treatments

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Conventional expression studies quantify messenger RNA (mRNA) transcript levels gene-by-gene. We recently showed that protein expression is modulated at a global scale by amino acid availability, suggesting that mRNA expression levels might be similarly affected by nucleobase supply. Re-analysis...

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4h ago